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The forward-looking statements in this report are based upon various assumptions, including without limitation, management's examination of historical operating trends, data contained in our records and data available from third parties. In our quest to find new medicines, we consistently rank among the world’s top companies investing in research and development. The easing of restrictions in Europe has also boosted optimism even as analysts keep a wary eye on alarming outbreaks prompted by new strains of the virus elsewhere in the world. Sydney, Seoul, Taipei all rose, while Singapore was flat and slumps rounded out morning trade in Jakarta and Manila. Furthermore, Novartis Gene Therapies entered into a manufacturing agreement with Massachusetts Eye and Ear and Massachusetts General Hospital to produce its novel genetic COVID-19 vaccine candidate called AAVCOVID8. The report published by the World Meteorological Organisation (WMO) also warns of a very high likelihood - a 90 per cent chance - of at least one year between 2021 and 2025 becoming the warmest on record, outstripping 2016’s record heat. A goalkeeper boycotting Myanmar's World Cup qualifiers has urged his teammates to "stand with the people" and raise the anti-junta three-finger salute in protest at the country's military coup. Globally, the surge is contributing to the highest food prices since 2014, according to the United Nations food agency, hitting poorer consumers particularly hard as they struggle to recover from economic shutdowns triggered by the COVID-19 pandemic. Using our live virus vaccine platform technology, MVA-BN®, we have created a diverse portfolio of proprietary and partnered product candidates designed to save and improve lives by unlocking the power of the immune system, including an Ebola vaccine, MVABEA®, which is licensed to the Janssen Pharmaceutical Companies of Johnson & Johnson. Trial participants will also receive an existing standard of care for COVID-19, including the FDA-approved antiviral remdesivir. “What really matters for gold are real rates,” he said, adding that central bankers would continue to keep rates low, which would be bullish for gold.Spot gold rose 0.1% to $1,898.96 an ounce by 12:48 p.m. in Singapore. These forward-looking statements are no guarantee of our future performance, and actual results and future developments may vary materially from those projected in the forward-looking statements. About DynavaxDynavax is a commercial stage biopharmaceutical company developing and commercializing novel vaccines. We are very excited about our acquisition of six VLCCs being built at Hyundai Heavy Industries in Korea. If the treatment has a positive risk-benefit profile, the study will enroll an additional 700 patients for further testing. He took some light slaps. With 11 Unit Trust funds to choose from, you can invest as low as RM500 with a flat sales charge of only 0.88%*. Sign up to follow @Novartis at https://twitter.com/novartisnewsFor Novartis multimedia content, please visit https://www.novartis.com/news/media-libraryFor questions about the site or required registration, please contact media.relations@novartis.com # # # Novartis Media RelationsE-mail: media.relations@novartis.com Michael MeoUS External Engagement, Novartis +1 862 274 5414michael.meo@novartis.com Julie MasowNovartis US External Communications+1 862 579 8456julie.masow@novartis.com Arzum UstunCommunications, Novartis Corporate Affairs and Global Health +41 79 108 5314arzum.ustun@novartis.com Novartis Investor RelationsCentral investor relations line: +41 61 324 7944E-mail: investor.relations@novartis.com Central North America Samir Shah +41 61 324 7944 Sloan Simpson +1 862 778 5052 Thomas Hungerbuehler +41 61 324 8425 Isabella Zinck +41 61 324 7188. 19 / 2021 i CDC. Eric Carle, author of well-known children’s book The Very Hungry Caterpillar, has died aged 91. Derniers chiffres du Coronavirus issus du CSSE 24/05/2021 (lundi 24 mai 2021). Le montant sera débité automatiquement de votre compte bancaire (autour du 20/23 de chaque mois). In February 2021, the European Commission (EC) granted marketing authorization for HEPLISAV B for the active immunization against hepatitis B virus infection (HBV) caused by all known subtypes of hepatitis B virus in adults 18 years of age and older. In addition, Novartis has signed an initial agreement to reserve capacity and implement the technology transfer for the production of the active pharmaceutical ingredient for Roche’s Actemra/RoActemra. SNOW earnings call for the period ending March 31, 2021. At Carsome, we take care of everything - you can even sell your car on the spot! Important EU/EEA Safety informationDo not receive HEPLISAV B if you have had a sudden life-threatening, allergic reaction after receiving HEPLISAV B in the past, or if you are allergic to any of components of this vaccine, including yeast. We expect the spot TCEs for the full second quarter of 2021 to be lower than the TCEs currently contracted, due to the impact of ballast days at the end of the second quarter as well as current freight rates.In March and April 2021, respectively, the Company took delivery of the LR2 newbuildings Front Fusion and Front Future. Current collaborations are focused on adjuvanted vaccines for COVID-19, pertussis and universal influenza. The Private Securities Litigation Reform Act of 1995 provides safe harbor protections for forward-looking statements, which include statements concerning plans, objectives, goals, strategies, future events or performance, and underlying assumptions and other statements, which are other than statements of historical facts. Important U.S. China’s exports to the U.S. have been strong due to the pandemic, U.S. stimulus payments and an economic rebound.Tai has previously said she expects China to live up to the commitments it made in the trade deal reached under the Trump administration and that the Biden government is focused on enforcing existing trade agreements and rules.Although those purchase targets look out of reach, agricultural goods may still prove a bright spot, with China purchasing corn for delivery later in the season to meet a domestic shortfall and a banner year for U.S. imports still on the cards.The stock market initially gained on the news of the call but that didn’t last. Frontline’s modern fleet allows for an agile approach to how we trade our ships, yielding returns above the key benchmarks. Silver was steady, platinum fell, while palladium advanced. Lars H. Barstad, Interim Chief Executive Officer of Frontline Management AS commented: “Despite challenging market conditions during the first quarter of 2021, Frontline manages to deliver a solid result. We undertake no obligation to publicly update or revise forward-looking statements to reflect subsequent events or circumstances after the date made, except as required by law. Important U.S. Safety Information (ISI)Do not administer HEPLISAV B to individuals with a history of severe allergic reaction (e.g., anaphylaxis) after a previous dose of any hepatitis B vaccine or to any component of HEPLISAV B, including yeast. "With a softening in the Chinese credit impulse and a resurgence of virus cases in India and Japan, topside ambitions continue to run into walls of profit-taking," he added. A former southeast Queensland mayor has been committed to stand trial on charges of official corruption and perjury.Luke Smith was the Logan City Council mayor when he was charged in 2018 following an investigation by the state's corruption watchdog. Latest Indian cyclone kills five, thousands homeless, Rising beef prices squeeze carnivores from Buenos Aires to California, Vic business groups demand lockdown compo. Dynavax has worldwide commercial rights to HEPLISAV B. Tokyo rose 0.2 percent after a shaky start with investors searching for new purchase cues. Thousands of people were homeless Thursday after the latest cyclone to hit Covid-ravaged India left a trail of destruction, although timely evacuations meant the death toll was limited to single figures. Meanwhile, New Zealand followed in the footsteps of Canada to flag a potential interest-rate increase next year as central banks begin to tip toe away from their emergency monetary settings.Gold has erased its 2021 losses amid signs of rising inflation and a potentially uneven economic recovery as some countries grappled with a resurgence in coronavirus cases. In currency markets, bitcoin dived more than 15 percent at one point over the weekend after reports that the US Treasury could crack down on digital money laundering, according to NAB analyst Rodrigo Catril. Thankfully, hepatitis B can be prevented with effective vaccination. Engine No. Appropriate medical treatment and supervision should be readily available in case of rare anaphylactic reactions following the administration of the vaccine. “Caterpillar is a book of hope: you, too, can grow up and grow wings.”. EMPATHY global multi-center Phase 2 - 3 study, recruiting patients with COVID-19 infection, aiming to prevent worsening symptoms and hospitalizationThe study plans to enroll 2100 patients, with 400 patients to be enrolled into Phase 2, followed by 1700 patients in Phase 3 Novartis has been granted an option from Molecular Partners to in-license global rights of ensovibep and MP0423 - DARPin® antiviral therapeutic candidates that are undergoing testing to target SARS-CoV-2 spike proteinDARPin® therapeutics well suited for a pandemic setting due to multi-specific target binding, long half-life for sustained activity and highly scalable production, compared to monoclonal antibodies Basel, May 27, 2021 — Novartis and Molecular Partners announced today the start of the clinical trial EMPATHY, a Phase 2 and 3 study, to explore the use of its novel DARPin® therapeutic candidate ensovibep (MP0420) for the treatment of COVID-19. We will remove this and make the necessary changes. Apply before 31 May 2021 to get RM800 MYDIN Vouchers & RM100 Cash Back. The Board of DirectorsFrontline Ltd.Hamilton, BermudaMay 26, 2021 Ola Lorentzon - Chairman and DirectorJohn Fredriksen - DirectorTor Svelland - Director James O'Shaughnessy - Director Questions should be directed to: Lars H. Barstad: Interim Chief Executive Officer, Frontline Management AS+47 23 11 40 37 Inger M. Klemp: Chief Financial Officer, Frontline Management AS+47 23 11 40 76 Forward-Looking Statements Matters discussed in this report may constitute forward-looking statements. The White House’s top official for Asia said this week that the U.S. is entering a period of intense competition with China as its government becomes ever more tightly controlled by President Xi Jinping.“The period that was broadly described as engagement has come to an end,” Kurt Campbell, the U.S. coordinator for Indo-Pacific affairs on the National Security Council, said Wednesday. The Health Secretary last night said he had not seen Mr Cummings’ seven-hour evidence to MPs as he was “saving lives” by dealing with the vaccination rollout. Novartis will conduct the clinical trial program for ensovibep, with Molecular Partners as sponsor of the studies. (Bloomberg) -- Gold steadied near the highest level in more than four months as investors weighed the future of monetary policy in a post-pandemic world.Federal Reserve Vice Chairman for Supervision Randal Quarles said on Wednesday that it will be important for the U.S. central bank to begin discussing in coming months plans to reduce its massive bond purchases if the economy continues to power ahead coming out of the pandemic. The first patient dose is expected to be administered in June 2021, with an interim analysis after 300 patients with mild-to-moderate disease. An angry Russell Westbrook had to be restrained after a Philadelphia76ers fan poured popcorn on his head as he went to the locker room for treatment late on Wednesday. The last time that happened was August 2020. These data confirmed the systemic administration of a multi-specific DARPin antiviral therapy to be safe and well tolerated and support plans for additional clinical work in patients diagnosed with COVID-19, as part of the EMPATHY trial. HEPLISAV B will complement and strengthen Bavarian Nordic’s commercial portfolio by leveraging its existing marketing and distribution network in Germany, which, in addition to the Company’s own vaccines for rabies and tick-borne encephalitis, also will include Valneva’s vaccines for Japanese Encephalitis and cholera as part of the mutual marketing and distribution agreement entered last year. The rates reported are for all days up until the last contracted discharge of cargo for each vessel in the quarter. A new climate update warns the odds of the world experiencing global annual temperatures that are 1.5C above pre-industrial levels in one of the next five years are increasing with time. “The overall challenges that we have with China are also still there and they are very large.”Tariff ReliefThe Liu-Tai call followed a staff-level phone talk that took place Tuesday night Washington time, according to a person familiar with the planning for the meeting. In addition, Novartis is active in several key cross-industry research initiatives, the COVID-19 Therapeutics Accelerator, coordinated by the Bill & Melinda Gates Foundation, Wellcome, and Mastercard as well as a COVID-19 directed partnership supported by the Innovative Medicines Initiative (IMI). COPENHAGEN, Denmark, May 27 2021 – Bavarian Nordic A/S (OMX: BAVA, OTC: BVNRY) has entered a partnership with Dynavax Technologies Corporation (Nasdaq: DVAX) a biopharmaceutical company focused on developing and commercializing novel vaccines for the marketing and distribution of their HEPLISAV B® [Hepatitis B Vaccine (Recombinant), Adjuvanted] Hepatitis B vaccine in Germany with an expected launch in the fourth quarter of 2021. This type of broad spectrum activity is essential for any treatment of relevance for patients with COVID-19,” said Patrick Amstutz, Chief Executive Officer, Molecular Partners. Because of the long incubation period of hepatitis B, it is possible for unrecognised HBV infection to be present at the time of immunisation. Important EU/EEA Product InformationHEPLISAV B is indicated for active immunisation against hepatitis B virus infection (HBV) caused by all known subtypes of hepatitis B virus in adults 18 years of age and older. “Novartis remains unwavering in our efforts to help combat COVID-19, including our support to deliver treatment options for patients around the globe,” said Dr. Lutz Hegemann, Group Head, Corporate Affairs and Global Health, Novartis. This report and any other written or oral statements made by us or on our behalf may include forward-looking statements, which reflect our current views with respect to future events and financial performance and are not intended to give any assurance as to future results. As a precautionary measure, it is preferable to avoid the use of HEPLISAV B during pregnancy. T&C apply. Au niveau mondial le nombre total de cas est de 167 004 521, le nombre de guérisons est de 103 819 152, le nombre de décès est de 3 466 943. The hepatitis B virus is 50 to 100 times more infectious than HIV,i and transmission is on the rise. Or worry about the massive paperwork? Forward-looking statements can generally be identified by words such as “potential,” “can,” “will,” “plan,” “may,” “could,” “would,” “expect,” “anticipate,” “seek,” “look forward,” “believe,” “committed,” “investigational,” “pipeline,” “launch,” or similar terms, or by express or implied discussions regarding potential marketing approvals, new indications or labeling for the investigational or approved products described in this press release, or regarding potential future revenues from such products. 4 weeks into standoff, there's a sliver of hope. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. We are hopeful the results of this clinical trial program will provide a reliable treatment option for patients with COVID-19.” Novartis believes a multi-solution strategy is needed to overcome COVID-19, one that utilizes a range of diagnostic and therapeutic options, depending on the needs of individual patients. Yahoo Finance: The latest news, analysis, money-saving and money-making tips. Millions of real salary data collected from government and companies - annual starting salaries, average salaries, payscale by company, job title, and city. Fed officials have pushed back against the threat that a spike in price pressures will prove lasting, while reassuring investors on the central bank’s accommodative stance.“With the reassurances from the banks, it is likely that even if inflation is higher than expected, the central bankers are still going to be dovish,” said Avtar Sandu, a senior manager for commodities at Phillip Futures Pte. The fundamentals of the tanker market remain firm, with an historic low order book and a significant part of the fleet challenged by tightening environmental regulations.” Average daily time charter equivalents ("TCEs")1 ($ per day) Spot TCE Spot TCE estimates % covered Estimated average daily cash BE rates for the remainder of the year Q1 2021 Q4 2020 2020 Q2 2021 2021 VLCC 19,000 17,200 54,500 18,100 70% 21,500 SMAX 15,200 9,800 35,600 13,600 63% 17,700 LR2 12,000 12,500 23,400 14,200 59% 15,900 The estimated average daily cash breakeven rates are the daily TCE rates the vessels must earn in order to cover operating expenses including dry docks, repayments of loans, interest on loans, bareboat hire, time charter hire and net general and administrative expenses for the remainder of the year. The EMPATHY clinical trial program is investigating the safety and efficacy of ensovibep in patients with COVID-19, who are in the early stages of infection, to prevent worsening symptoms and hospitalization. Immunocompromised persons may have a diminished immune response to HEPLISAV B. Ryan Spencer, Chief Executive Officer of Dynavax, commented: “We are excited to work with Bavarian Nordic on the commercialization of HEPLISAV B in Germany. This reflects our business model, with high focus on efficiency, quality, and cost throughout the organization. With less economic data on the calendar in the days ahead and the Fed in a communications blackout ahead of its April 28 rates meeting, "it might be a week for spring housekeeping in the markets," he added. The most common patient reported adverse reactions reported within 7 days of vaccination were injection site pain (23% to 39%), fatigue (11% to 17%) and headache (8% to 17%). With a two-dose regimen that takes only one month to complete and a statistically significantly higher seroprotection rate in head-to-head clinical trials, HEPLISAV B provides a unique opportunity to address known challenges with compliance, while delivering higher levels of protection compared to the three-dose regimen of the comparator vaccine.” Paul Chaplin, President and CEO of Bavarian Nordic, commented: “We are pleased to expand our commercial footprint in the largest EU market by adding a complementary product to our marketing and distribution and we look forward to assisting Dynavax in a successful market entry in Europe later this year.” About Hepatitis BHepatitis B is a viral disease of the liver that can become chronic and lead to cirrhosis, liver cancer and death. T&C apply. When used in this document, the words "believe," "anticipate," "intend," "estimate," "forecast," "project," "plan," "potential," "will," "may," "should," "expect" and similar expressions, terms or phrases may identify forward-looking statements. Over the life of a voyage there is no difference in the total revenues and costs to be recognized as compared to a discharge-to-discharge basis. Adjusted net income of $8.8 million, or $0.04 per diluted share for the first quarter of 2021.Reported total operating revenues of $194.0 million for the first quarter of 2021.Reported spot TCEs for VLCCs, Suezmax and LR2 tankers in the first quarter of 2021 were $19,000, $15,200 and $12,000 per day, respectively.For the second quarter of 2021, we estimate spot TCE on a load-to-discharge basis of $18,100 contracted for 70% of vessel days for VLCCs, $13,600 contracted for 63% of vessel days for Suezmax tankers and $14,200 contracted for 59% of vessel days for LR2 tankers. Attachment 1st Quarter 2021 Results, Your Dreams Come True Here. Ces actions sont ensuite transférées pour être gérées dans le FCPE CASTOR. Novartis is committed to donating US $40 million to help communities affected by the pandemic around the world. Ties have deteriorated over the past year or more on almost every other topic, with clashes over human-rights concerns including allegations of forced labor in China’s western Xinjiang region; Taiwan; the crackdown in Hong Kong; Beijing’s purchases of oil from sanctioned Iran; and the long-running disputes over the South China and East China Seas.The trade deal should be seen in the context of “the overall U.S.-China trade, and economic relationship which is very, very challenging,” Tai told Reuters in an interview Wednesday. Novartis is on Twitter. Bitcoin hit a record high above $62,000 last week ahead of the Wall Street debut of cryptocurrency exchange Coinbase, despite concerns about a bubble and the sustainability of the digital currency market. The Bloomberg Dollar Spot Index was flat, after rising 0.3% on Wednesday.More stories like this are available on bloomberg.comSubscribe now to stay ahead with the most trusted business news source.©2021 Bloomberg L.P. ContactsEurope: Rolf Sass Sørensen, Vice President Investor Relations, Tel: +45 61 77 47 43US: Graham Morrell, Paddock Circle Advisors, graham@paddockcircle.com, Tel: +1 781 686 9600 Company Announcement no. Frontline Ltd. (the “Company” or “Frontline”), today reported unaudited results for the three months ended March 31, 2021: Highlights Net income of $28.9 million, or $0.15 per diluted share for the first quarter of 2021. In our labs, we have started a collaborative, longer-term drug discovery effort to develop the first oral medicines for COVID-19 and other coronaviruses. Oil benchmarks were down despite energy markets enjoying a boost from industry forecasts and tensions between Washington, Tehran and Russia, Innes said. Vaccination during pregnancy should only be performed if the risk-benefit ratio at the individual level outweighs possible risks for the fetus. For more information visit www.bavarian-nordic.com. Nor can there be any guarantee that such products will be commercially successful in the future. "The Tokyo market may take a wait-and-see stance before the corporate earnings season kicks into high gear" later this week, SBI Securities said in a note. In March 2021, Molecular Partners reported positive initial Phase 1 results in healthy volunteers. Our commercial product portfolio furthermore contains the market-leading vaccine Rabipur®/RabAvert® against rabies and Encepur® against tick-borne encephalitis. Derniers chiffres du Coronavirus issus du CSSE 24/05/2021 pour le pays France. Signs of an allergic reaction may include itchy skin, rash, shortness of breath and swelling of the face or tongue. More information about the Novartis response to COVID-19 is available at www.novartis.com/COVID-19. There is no cure for hepatitis B, but effective vaccination can prevent the disease. “Reaching this important clinical milestone is not only a key step to combat this virus, but also validating our DARPin approach to generate multispecific antiviral therapies in the fight against global pandemics.” Initial findings from the Phase 1 trial of ensovibep showed it to be safe and well tolerated with no significant adverse events. The strong overlap with the existing target audience within general practitioners, occupational health groups and travel medicine specialists provides a good strategic fit and clear commercial synergies for the dedicated sales force, Bavarian Nordic has established in Germany. Sell Your Car Conveniently In 24 Hours Here! Those eligible for the EMPATHY trial are adults, over the age of 18, with a positive SARS-CoV-2 antigen test and who are experiencing at least two pre-determined mild/moderate symptoms of COVID-19 within 7 days of their diagnosis. Information for research of yearly salaries, wage level, bonus and compensation data comparison.

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